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Lack of Endothelial α1AMPK Reverses the Vascular Protective Effects of Exercise by Causing eNOS Uncoupling
Voluntary exercise training is an effective way to prevent cardiovascular disease, since it results in increased NO bioavailability and decreased reactive oxygen species (ROS) production. AMP-activated protein kinase (AMPK), especially its α1AMPK subunit, modulates ROS-dependent vascular homeostasis...
Autores principales: | Jansen, Thomas, Kvandová, Miroslava, Schmal, Isabella, Kalinovic, Sanela, Stamm, Paul, Kuntic, Marin, Foretz, Marc, Viollet, Benoit, Daiber, Andreas, Oelze, Matthias, Keaney, John F., Münzel, Thomas, Schulz, Eberhard, Kröller-Schön, Swenja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750041/ https://www.ncbi.nlm.nih.gov/pubmed/34943078 http://dx.doi.org/10.3390/antiox10121974 |
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