The Alpha-Synuclein RT-QuIC Products Generated by the Olfactory Mucosa of Patients with Parkinson’s Disease and Multiple System Atrophy Induce Inflammatory Responses in SH-SY5Y Cells

Parkinson’s disease (PD) and multiple system atrophy (MSA) are caused by two distinct strains of disease-associated α-synuclein (αSyn(D)). Recently, we have shown that olfactory mucosa (OM) samples of patients with PD and MSA can seed the aggregation of recombinant α-synuclein by means of Real-Time...

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Detalles Bibliográficos
Autores principales: De Luca, Chiara Maria Giulia, Consonni, Alessandra, Cazzaniga, Federico Angelo, Bistaffa, Edoardo, Bufano, Giuseppe, Quitarrini, Giorgia, Celauro, Luigi, Legname, Giuseppe, Eleopra, Roberto, Baggi, Fulvio, Giaccone, Giorgio, Moda, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750063/
https://www.ncbi.nlm.nih.gov/pubmed/35011649
http://dx.doi.org/10.3390/cells11010087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750063/
https://www.ncbi.nlm.nih.gov/pubmed/35011649
http://dx.doi.org/10.3390/cells11010087

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