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HPVE6-USP46 Mediated Cdt2 Stabilization Reduces Set8 Mediated H4K20-Methylation to Induce Gene Expression Changes

SIMPLE SUMMARY: Cervical cancer is one of the most common cancers in women. More than 95% of the cervical cancers are caused by the human papilloma viruses. Earlier we had identified a protein target, USP46 that can be inhibited to block the cancer growth. We found that the viral E6 and human USP46...

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Detalles Bibliográficos
Autores principales: Kiran, Shashi, Wilson, Briana, Saha, Shekhar, Graff, Julia Ann, Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750077/
https://www.ncbi.nlm.nih.gov/pubmed/35008200
http://dx.doi.org/10.3390/cancers14010030