Cargando…
Potassium Effects on NCC Are Attenuated during Inhibition of Cullin E3–Ubiquitin Ligases
The thiazide-sensitive sodium chloride cotransporter (NCC) plays a vital role in maintaining sodium (Na(+)) and potassium (K(+)) homeostasis. NCC activity is modulated by with-no-lysine kinases 1 and 4 (WNK1 and WNK4), the abundance of which is controlled by the RING-type E3 ligase Cullin 3 (Cul3) a...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750104/ https://www.ncbi.nlm.nih.gov/pubmed/35011657 http://dx.doi.org/10.3390/cells11010095 |