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Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression

SIMPLE SUMMARY: Colorectal cancer is the second leading cause of cancer-related death in the world. Upregulation of fatty acid metabolism is a hallmark of cancer and recent studies demonstrate that blocking fatty acid uptake is a promising therapeutic strategy. We have previously shown that CD36, a...

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Detalles Bibliográficos
Autores principales: Drury, James, Rychahou, Piotr G., Kelson, Courtney O., Geisen, Mariah E., Wu, Yuanyuan, He, Daheng, Wang, Chi, Lee, Eun Y., Evers, B. Mark, Zaytseva, Yekaterina Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750155/
https://www.ncbi.nlm.nih.gov/pubmed/35008415
http://dx.doi.org/10.3390/cancers14010252