Genome-Wide RNAi Screening Identifies Novel Pathways/Genes Involved in Oxidative Stress and Repurposable Drugs to Preserve Cystic Fibrosis Airway Epithelial Cell Integrity

Recurrent infection-inflammation cycles in cystic fibrosis (CF) patients generate a highly oxidative environment, leading to progressive destruction of the airway epithelia. The identification of novel modifier genes involved in oxidative stress susceptibility in the CF airways might contribute to d...

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Detalles Bibliográficos
Autores principales: Checa, Javier, Martínez-González, Itziar, Maqueda, Maria, Mosquera, Jose Luis, Aran, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750174/
https://www.ncbi.nlm.nih.gov/pubmed/34943039
http://dx.doi.org/10.3390/antiox10121936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750174/
https://www.ncbi.nlm.nih.gov/pubmed/34943039
http://dx.doi.org/10.3390/antiox10121936

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