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Endothelial Adenosine Monophosphate-Activated Protein Kinase-Alpha1 Deficiency Potentiates Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension

Bronchopulmonary dysplasia and pulmonary hypertension, or BPD-PH, are serious chronic lung disorders of prematurity, without curative therapies. Hyperoxia, a known causative factor of BPD-PH, activates adenosine monophosphate-activated protein kinase (AMPK) α1 in neonatal murine lungs; however, whet...

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Detalles Bibliográficos
Autores principales: Elsaie, Ahmed, Menon, Renuka T., Shrestha, Amrit K., Gowda, Sharada H., Varghese, Nidhy P., Barrios, Roberto J., Blanco, Cynthia L., Konduri, Girija G., Shivanna, Binoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750184/
https://www.ncbi.nlm.nih.gov/pubmed/34943016
http://dx.doi.org/10.3390/antiox10121913