A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence

Many proteins are causative for inherited partial lipodystrophies, including lamins, the essential constituents of the nuclear envelope scaffold called the lamina. By performing high throughput sequencing on a panel of genes involved in lipodystrophies, we identified a heterozygous mutation in LMNB2...

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Detalles Bibliográficos
Autores principales: Varlet, Alice-Anaïs, Desgrouas, Camille, Jebane, Cécile, Bonello-Palot, Nathalie, Bourgeois, Patrice, Levy, Nicolas, Helfer, Emmanuèle, Dubois, Noémie, Valero, René, Badens, Catherine, Beliard, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750194/
https://www.ncbi.nlm.nih.gov/pubmed/35011612
http://dx.doi.org/10.3390/cells11010050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750194/
https://www.ncbi.nlm.nih.gov/pubmed/35011612
http://dx.doi.org/10.3390/cells11010050

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