N-Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization

Leveraging the T cell immunity against tumors represents a revolutionary type of cancer therapy. 4-1BB is a well-characterized costimulatory immune receptor existing on activated T cells and mediating their proliferation and cytotoxicity under infectious diseases and cancers. Despite the accumulatin...

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Detalles Bibliográficos
Autores principales: Sun, Ruoxuan, Kim, Alyssa Min Jung, Murray, Allison A., Lim, Seung-Oe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750214/
https://www.ncbi.nlm.nih.gov/pubmed/35011724
http://dx.doi.org/10.3390/cells11010162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750214/
https://www.ncbi.nlm.nih.gov/pubmed/35011724
http://dx.doi.org/10.3390/cells11010162

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