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N-Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization
Leveraging the T cell immunity against tumors represents a revolutionary type of cancer therapy. 4-1BB is a well-characterized costimulatory immune receptor existing on activated T cells and mediating their proliferation and cytotoxicity under infectious diseases and cancers. Despite the accumulatin...
Autores principales: | Sun, Ruoxuan, Kim, Alyssa Min Jung, Murray, Allison A., Lim, Seung-Oe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750214/ https://www.ncbi.nlm.nih.gov/pubmed/35011724 http://dx.doi.org/10.3390/cells11010162 |
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