Shift in G(1)-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation

The current view of the involvement of PI3-kinases in checkpoint responses after DNA damage is that ATM is the key regulator of G(1)-, S- or G(2)-phase checkpoints, that ATR is only partly involved in the regulation of S- and G(2)-phase checkpoints and that DNA-PKcs is not involved in checkpoint reg...

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Detalles Bibliográficos
Autores principales: Li, Fanghua, Mladenov, Emil, Dueva, Rositsa, Stuschke, Martin, Timmermann, Beate, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750242/
https://www.ncbi.nlm.nih.gov/pubmed/35011623
http://dx.doi.org/10.3390/cells11010063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750242/
https://www.ncbi.nlm.nih.gov/pubmed/35011623
http://dx.doi.org/10.3390/cells11010063

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