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Shift in G(1)-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation
The current view of the involvement of PI3-kinases in checkpoint responses after DNA damage is that ATM is the key regulator of G(1)-, S- or G(2)-phase checkpoints, that ATR is only partly involved in the regulation of S- and G(2)-phase checkpoints and that DNA-PKcs is not involved in checkpoint reg...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750242/ https://www.ncbi.nlm.nih.gov/pubmed/35011623 http://dx.doi.org/10.3390/cells11010063 |