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Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy

Doxorubicin (Dox) is known to cause heart failure in some cancer patients. Despite extensive studies over the past half century, the subcellular basis of Dox-induced cardiomyopathy (DIC) is still elusive. Earlier, we suggested that Dox causes a delayed activation of unfolded protein response (UPR) w...

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Detalles Bibliográficos
Autores principales: Bagchi, Ashim K., Malik, Akshi, Akolkar, Gauri, Jassal, Davinder S., Singal, Pawan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750247/
https://www.ncbi.nlm.nih.gov/pubmed/34943000
http://dx.doi.org/10.3390/antiox10121897