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Whole-Exome Sequencing of HPV Positive Tonsillar and Base of Tongue Squamous Cell Carcinomas Reveals a Global Mutational Pattern along with Relapse-Specific Somatic Variants

SIMPLE SUMMARY: To better prevent/combat recurrence and identify predictive/targetable markers upon diagnosis, we performed whole-exome sequencing (WES) of primary tumours and relapses of human papillomavirus positive (HPV(+)) tonsillar and base of tongue cancer (TSCC/BOTSCC) on patients treated wit...

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Detalles Bibliográficos
Autores principales: Ährlund-Richter, Andreas, Holzhauser, Stefan, Dalianis, Tina, Näsman, Anders, Mints, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750256/
https://www.ncbi.nlm.nih.gov/pubmed/35008243
http://dx.doi.org/10.3390/cancers14010077