High Plus Low Dose Radiation Strategy in Combination with TIGIT and PD1 Blockade to Promote Systemic Antitumor Responses

SIMPLE SUMMARY: This study combines a novel strategy of radiotherapy that utilizes high- and low- dose radiation with immune oncology agents (anti-TIGIT and anti-PD1 monoclonal antibodies) in order to overcome the inhibitory tumor stroma and battle tumors systemically. The findings from this work wi...

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Detalles Bibliográficos
Autores principales: Barsoumian, Hampartsoum B., Sezen, Duygu, Menon, Hari, Younes, Ahmed I., Hu, Yun, He, Kewen, Puebla-Osorio, Nahum, Wasley, Mark, Hsu, Ethan, Patel, Roshal R., Yang, Liangpeng, Cortez, Maria A., Welsh, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750272/
https://www.ncbi.nlm.nih.gov/pubmed/35008385
http://dx.doi.org/10.3390/cancers14010221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750272/
https://www.ncbi.nlm.nih.gov/pubmed/35008385
http://dx.doi.org/10.3390/cancers14010221

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