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High Plus Low Dose Radiation Strategy in Combination with TIGIT and PD1 Blockade to Promote Systemic Antitumor Responses
SIMPLE SUMMARY: This study combines a novel strategy of radiotherapy that utilizes high- and low- dose radiation with immune oncology agents (anti-TIGIT and anti-PD1 monoclonal antibodies) in order to overcome the inhibitory tumor stroma and battle tumors systemically. The findings from this work wi...
Autores principales: | Barsoumian, Hampartsoum B., Sezen, Duygu, Menon, Hari, Younes, Ahmed I., Hu, Yun, He, Kewen, Puebla-Osorio, Nahum, Wasley, Mark, Hsu, Ethan, Patel, Roshal R., Yang, Liangpeng, Cortez, Maria A., Welsh, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750272/ https://www.ncbi.nlm.nih.gov/pubmed/35008385 http://dx.doi.org/10.3390/cancers14010221 |
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