Jak2 Inhibitor AG490 Improved Poststroke Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat Model of Ischemic Stroke

Poststroke hyperglycemia and inflammation have been implicated in the pathogenesis of stroke. Janus Kinase 2 (Jak2), a catalytic signaling component for cytokine receptors such as Interleukin-6 (IL-6), has inflammatory and metabolic properties. This study aimed to investigate the roles of Jak2 in po...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Yu, Lin, Shih-Yi, Chang, Cheng-Yi, Wu, Chih-Cheng, Chen, Wen-Ying, Liao, Su-Lan, Chen, Yu-Fan, Wang, Wen-Yi, Chen, Chun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750281/
https://www.ncbi.nlm.nih.gov/pubmed/34943061
http://dx.doi.org/10.3390/antiox10121958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750281/
https://www.ncbi.nlm.nih.gov/pubmed/34943061
http://dx.doi.org/10.3390/antiox10121958

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