Role of the Redox State of Human Peroxiredoxin-5 on Its TLR4-Activating DAMP Function

Human peroxiredoxin-5 (PRDX5) is a unique redox-sensitive protein that plays a dual role in brain ischemia-reperfusion injury. While intracellular PRDX5 has been reported to act as a neuroprotective antioxidative enzyme by scavenging peroxides, once released extracellularly from necrotic brain cells...

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Detalles Bibliográficos
Autores principales: Poncin, Mégane A., Van Meerbeeck, Pierre, Simpson, Joshua D., Clippe, André, Tyckaert, François, Bouillenne, Fabrice, Degand, Hervé, Matagne, André, Morsomme, Pierre, Knoops, Bernard, Alsteens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750366/
https://www.ncbi.nlm.nih.gov/pubmed/34943005
http://dx.doi.org/10.3390/antiox10121902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750366/
https://www.ncbi.nlm.nih.gov/pubmed/34943005
http://dx.doi.org/10.3390/antiox10121902

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