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The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression

Neural stem cells (NSCs), crucial for memory in the adult brain, are also pivotal to buffer depressive behavior. However, the mechanisms underlying the boost in NSC activity throughout life are still largely undiscovered. Here, we aimed to explore the role of deacetylase Sirtuin 3 (SIRT3), a central...

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Detalles Bibliográficos
Autores principales: Santos, Sónia Sá, Moreira, João B., Costa, Márcia, Rodrigues, Rui S., Sebastião, Ana M., Xapelli, Sara, Solá, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750385/
https://www.ncbi.nlm.nih.gov/pubmed/35011652
http://dx.doi.org/10.3390/cells11010090