Caspase-1-Dependent Pyroptosis Mediates Adjuvant Activity of Platycodin D as an Adjuvant for Intramuscular Vaccines

Platycodin D (PD) is a potent adjuvant with dual Th1 and Th2 potentiating activity, but its mechanisms of action remain unclear. Here, the C2C12 myoblast cell line and mice were used as in vitro and in vivo models to identify potential signaling pathways involved in the adjuvant activity of PD. PD i...

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Detalles Bibliográficos
Autores principales: Zhu, Liyan, Han, Ziyi, He, Yanfei, Sun, Hongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750424/
https://www.ncbi.nlm.nih.gov/pubmed/35011696
http://dx.doi.org/10.3390/cells11010134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750424/
https://www.ncbi.nlm.nih.gov/pubmed/35011696
http://dx.doi.org/10.3390/cells11010134

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