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TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated the as yet unknown roles of calcium signaling and autophagy regulatory protei...

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Detalles Bibliográficos
Autores principales: Airiau, Kelly, Vacher, Pierre, Micheau, Olivier, Prouzet-Mauleon, Valerie, Kroemer, Guido, Moosavi, Mohammad Amin, Djavaheri-Mergny, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750441/
https://www.ncbi.nlm.nih.gov/pubmed/35011619
http://dx.doi.org/10.3390/cells11010057