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Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli

Tet methylcytosine dioxygenase 2 (Tet2) mediates demethylation of DNA. We here sought to determine the expression and function of Tet2 in macrophages upon exposure to lipopolysaccharide (LPS), and in the host response to LPS induced lung and peritoneal inflammation, and during Escherichia (E.) coli...

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Detalles Bibliográficos
Autores principales: Qin, Wanhai, Brands, Xanthe, Matsumoto, Hisatake, Butler, Joe M., van’t Veer, Cornelis, de Vos, Alex F., Roelofs, Joris J. T. H., Scicluna, Brendon P., van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750455/
https://www.ncbi.nlm.nih.gov/pubmed/35011643
http://dx.doi.org/10.3390/cells11010082