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Discovery of Sulforaphane as an Inducer of Ferroptosis in U-937 Leukemia Cells: Expanding Its Anticancer Potential

SIMPLE SUMMARY: Ferroptosis and necroptosis are two non-apoptotic programmed cell death pathways with increasing therapeutic potential. The isothiocyanate sulforaphane (SFN) is a well-known naturally derived anticancer compound with remarkable pro-apoptotic activity. Its ability to promote non-apopt...

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Detalles Bibliográficos
Autores principales: Greco, Giulia, Schnekenburger, Michael, Catanzaro, Elena, Turrini, Eleonora, Ferrini, Fabio, Sestili, Piero, Diederich, Marc, Fimognari, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750507/
https://www.ncbi.nlm.nih.gov/pubmed/35008240
http://dx.doi.org/10.3390/cancers14010076