Cargando…

Celastrol and Melatonin Modify SIRT1, SIRT6 and SIRT7 Gene Expression and Improve the Response of Human Granulosa-Lutein Cells to Oxidative Stress

An excess of oxidative stress (OS) may affect several physiological processes fundamental to reproduction. SIRT1, SIRT6 and SIRT7 are involved in protection stress systems caused by OS, and they can be activated by antioxidants such as celastrol or melatonin. In this study, we evaluate SIRT1, SIRT6...

Descripción completa

Detalles Bibliográficos
Autores principales: Martín-Ramírez, Rita, González-Fernández, Rebeca, Hernández, Jairo, Martín-Vasallo, Pablo, Palumbo, Angela, Ávila, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750604/
https://www.ncbi.nlm.nih.gov/pubmed/34942974
http://dx.doi.org/10.3390/antiox10121871