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Carnosic Acid Attenuates the Free Fatty Acid-Induced Insulin Resistance in Muscle Cells and Adipocytes

Elevated blood free fatty acids (FFAs), as seen in obesity, impair insulin action leading to insulin resistance and Type 2 diabetes mellitus. Several serine/threonine kinases including JNK, mTOR, and p70 S6K cause serine phosphorylation of the insulin receptor substrate (IRS) and have been implicate...

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Detalles Bibliográficos
Autores principales: Den Hartogh, Danja J., Vlavcheski, Filip, Giacca, Adria, MacPherson, Rebecca E. K., Tsiani, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750606/
https://www.ncbi.nlm.nih.gov/pubmed/35011728
http://dx.doi.org/10.3390/cells11010167