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Mitophagy: Molecular Mechanisms, New Concepts on Parkin Activation and the Emerging Role of AMPK/ULK1 Axis

Mitochondria are multifunctional subcellular organelles essential for cellular energy homeostasis and apoptotic cell death. It is, therefore, crucial to maintain mitochondrial fitness. Mitophagy, the selective removal of dysfunctional mitochondria by autophagy, is critical for regulating mitochondri...

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Detalles Bibliográficos
Autores principales: Iorio, Roberto, Celenza, Giuseppe, Petricca, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750607/
https://www.ncbi.nlm.nih.gov/pubmed/35011593
http://dx.doi.org/10.3390/cells11010030