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A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy

SIMPLE SUMMARY: Metabolic-associated fatty liver disease (MAFLD) is a chronic liver disease associated with obesity, diabetes mellitus type 2 (DM2), and hyperlipidemia. It can also progress to end-stage hepatocellular carcinoma (HCC); the underlying mechanisms are still unknown, but endogenous (i.e....

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Detalles Bibliográficos
Autores principales: Guo, Feifei, Estévez-Vázquez, Olga, Benedé-Ubieto, Raquel, Maya-Miles, Douglas, Zheng, Kang, Gallego-Durán, Rocío, Rojas, Ángela, Ampuero, Javier, Romero-Gómez, Manuel, Philip, Kaye, Egbuniwe, Isioma U., Chen, Chaobo, Simon, Jorge, Delgado, Teresa C., Martínez-Chantar, María Luz, Sun, Jie, Reissing, Johanna, Bruns, Tony, Lamas-Paz, Arantza, del Moral, Manuel Gómez, Woitok, Marius Maximilian, Vaquero, Javier, Regueiro, José R., Liedtke, Christian, Trautwein, Christian, Bañares, Rafael, Cubero, Francisco Javier, Nevzorova, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750626/
https://www.ncbi.nlm.nih.gov/pubmed/35008356
http://dx.doi.org/10.3390/cancers14010192