Immune Checkpoint Inhibitors in Mismatch Repair Proficient/Microsatellite Stable Metastatic Colorectal Cancer Patients: Insights from the AtezoTRIBE and MAYA Trials

SIMPLE SUMMARY: Immune-checkpoint inhibitors (ICI) show modest activity and efficacy in microsatellite stable (MSS) metastatic colorectal cancer (mCRC) patients harbouring a proficient mismatch repair system (pMMR). Recently, two phase 2 trials -AtezoTRIBE and MAYA- have challenged this dogma throug...

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Detalles Bibliográficos
Autores principales: Germani, Marco Maria, Moretto, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750658/
https://www.ncbi.nlm.nih.gov/pubmed/35008215
http://dx.doi.org/10.3390/cancers14010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750658/
https://www.ncbi.nlm.nih.gov/pubmed/35008215
http://dx.doi.org/10.3390/cancers14010052

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