Retrotransposons Down- and Up-Regulation in Aging Somatic Tissues

The transposon theory of aging hypothesizes the activation of transposable elements (TEs) in somatic tissues with age, leading to a shortening of the lifespan. It is thought that TE activation in aging produces an increase in DNA double-strand breaks, contributing to genome instability and promoting...

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Detalles Bibliográficos
Autores principales: Giordani, Giorgia, Cavaliere, Valeria, Gargiulo, Giuseppe, Lattanzi, Giovanna, Andrenacci, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750722/
https://www.ncbi.nlm.nih.gov/pubmed/35011640
http://dx.doi.org/10.3390/cells11010079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750722/
https://www.ncbi.nlm.nih.gov/pubmed/35011640
http://dx.doi.org/10.3390/cells11010079

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