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Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing

The Pax-5 gene encodes a transcription factor that is essential for B-cell commitment and maturation. However, Pax-5 deregulation is associated with various cancer lesions, notably hematopoietic cancers. Mechanistically, studies have characterized genetic alterations within the Pax-5 locus that resu...

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Detalles Bibliográficos
Autores principales: Beauregard, Annie-Pier, Hannay, Brandon, Gharib, Ehsan, Crapoulet, Nicolas, Finn, Nicholas, Guerrette, Roxann, Ouellet, Amélie, Robichaud, Gilles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750734/
https://www.ncbi.nlm.nih.gov/pubmed/35011638
http://dx.doi.org/10.3390/cells11010076