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The Effect of Direct and Indirect EZH2 Inhibition in Rhabdomyosarcoma Cell Lines

SIMPLE SUMMARY: Rhabdomyosarcoma is the most common soft tissue tumor in children. Its two major subtypes show epigenetic alterations that are associated with poor prognosis. Therefore, targeting these epigenetic alterations by pharmacological intervention could be a therapeutic approach. We investi...

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Detalles Bibliográficos
Autores principales: Schmidt, Andreas, Behrendt, Lucas, Eybe, Jana, Warmann, Steven W., Schleicher, Sabine, Fuchs, Joerg, Schmid, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750739/
https://www.ncbi.nlm.nih.gov/pubmed/35008205
http://dx.doi.org/10.3390/cancers14010041