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Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation

Williams syndrome (WS) is a multisystem neurodevelopmental disorder caused by a de novo hemizygous deletion of ~26 genes from chromosome 7q11.23, among them the general transcription factor II-I (GTF2I). By studying a novel murine model for the hypersociability phenotype associated with WS, we previ...

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Detalles Bibliográficos
Autores principales: Grad, Meitar, Nir, Ariel, Levy, Gilad, Trangle, Sari Schokoroy, Shapira, Guy, Shomron, Noam, Assaf, Yaniv, Barak, Boaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750756/
https://www.ncbi.nlm.nih.gov/pubmed/35011720
http://dx.doi.org/10.3390/cells11010158