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Glucose Activates Lysine-Specific Demethylase 1 through the KEAP1/p62 Pathway

Endometrial cancer incidence increases annually. Several risk factors, including high glucose intake, are associated with endometrial cancer. We investigated whether glucose affects lysine-specific demethylase 1 (LSD1) expression and the responsible molecular mechanisms. A high concentration of gluc...

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Detalles Bibliográficos
Autores principales: Lin, Chiao-Yun, Chang, Chen-Bin, Wu, Ren-Chin, Chao, Angel, Lee, Yun-Shien, Tsai, Chi-Neu, Chen, Chih-Hao, Yen, Chih-Feng, Tsai, Chia-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750790/
https://www.ncbi.nlm.nih.gov/pubmed/34942999
http://dx.doi.org/10.3390/antiox10121898