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The Cytoplasmic Dynein Associated Protein NDE1 Regulates Osteoclastogenesis by Modulating M-CSF and RANKL Signaling Pathways

Cytoskeleton organization and lysosome secretion play an essential role in osteoclastogenesis and bone resorption. The cytoplasmic dynein is a molecular motor complex that regulates microtubule dynamics and transportation of cargos/organelles, including lysosomes along the microtubules. LIS1, NDE1,...

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Detalles Bibliográficos
Autores principales: Das, Bhaba K., Gogoi, Jyoti, Kannan, Aarthi, Gao, Ling, Xing, Weirong, Mohan, Subburaman, Zhao, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750859/
https://www.ncbi.nlm.nih.gov/pubmed/35011575
http://dx.doi.org/10.3390/cells11010013