Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners

High eosinophil (EOS) counts are a key feature of eosinophilic asthma. EOS notably affect asthmatic response by generating several lipid mediators. Mice have been utilized in hopes of defining new pharmacological targets to treat asthma. However, many pinpointed targets in mice did not translate int...

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Detalles Bibliográficos
Autores principales: Archambault, Anne-Sophie, Brassard, Julyanne, Bernatchez, Émilie, Martin, Cyril, Di Marzo, Vincenzo, Laviolette, Michel, Boulet, Louis-Philippe, Blanchet, Marie-Renée, Flamand, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750928/
https://www.ncbi.nlm.nih.gov/pubmed/35011703
http://dx.doi.org/10.3390/cells11010141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750928/
https://www.ncbi.nlm.nih.gov/pubmed/35011703
http://dx.doi.org/10.3390/cells11010141

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