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Auger Emitter Conjugated PARP Inhibitor for Therapy in Triple Negative Breast Cancers: A Comparative In-Vitro Study

SIMPLE SUMMARY: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer, with a high recurrence rate. Since treatment of BRCA(mut) TNBC patients with PARP inhibitor (PARPi), targeting the nuclear protein PARP1, shows varied responses, its therapeutic efficacy is currently eval...

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Detalles Bibliográficos
Autores principales: Sankaranarayanan, Ramya Ambur, Peil, Jennifer, Vogg, Andreas T. J., Bolm, Carsten, Terhorst, Steven, Classen, Arno, Bauwens, Matthias, Maurer, Jochen, Mottaghy, Felix, Morgenroth, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750932/
https://www.ncbi.nlm.nih.gov/pubmed/35008392
http://dx.doi.org/10.3390/cancers14010230