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Genetic variations from successive whole genome sequencing during COVID-19 treatment in five individuals
We report multiple single nucleotide polymorphism taken at different time interval during treatment of COVID-19. Gene sequencing showed mutation within ORF1b at position P314L. Mutation at this point has been shown to impose structural remodelling that increases the affinity for remdesivir binding a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750952/ https://www.ncbi.nlm.nih.gov/pubmed/35035981 http://dx.doi.org/10.1016/j.nmni.2022.100950 |