Genetic variations from successive whole genome sequencing during COVID-19 treatment in five individuals

We report multiple single nucleotide polymorphism taken at different time interval during treatment of COVID-19. Gene sequencing showed mutation within ORF1b at position P314L. Mutation at this point has been shown to impose structural remodelling that increases the affinity for remdesivir binding a...

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Detalles Bibliográficos
Autores principales: Hemachudha, P., Petcharat, S., Ampoot, W., Ponpinit, T., Paitoonpong, L., Hemachudha, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750952/
https://www.ncbi.nlm.nih.gov/pubmed/35035981
http://dx.doi.org/10.1016/j.nmni.2022.100950

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