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Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis

BACKGROUND: Altered cerebrovascular function and accumulation of amyloid-β (Aβ) after traumatic brain injury (TBI) can contribute to chronic neuropathology and increase the risk for Alzheimer’s disease (AD). TBI due to a blast-induced shock wave (bTBI) adversely affects the neurovascular unit (NVU)...

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Detalles Bibliográficos
Autores principales: Clark, Alexander T., Abrahamson, Eric E., Harper, Matthew M., Ikonomovic, Milos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751260/
https://www.ncbi.nlm.nih.gov/pubmed/35012589
http://dx.doi.org/10.1186/s12987-021-00301-z