Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells

BACKGROUND: Spinal cord motor neurons (MNs) from human iPS cells (iPSCs) have wide applications in disease modeling and therapeutic development for amyotrophic lateral sclerosis (ALS) and other MN-associated neurodegenerative diseases. We need highly efficient MN differentiation strategies for gener...

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Detalles Bibliográficos
Autores principales: Li, Qian, Feng, Yi, Xue, Yingchao, Zhan, Xiping, Fu, Yi, Gui, Gege, Zhou, Weiqiang, Richard, Jean-Philippe, Taga, Arens, Li, Pan, Mao, Xiaobo, Maragakis, Nicholas J., Ying, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751314/
https://www.ncbi.nlm.nih.gov/pubmed/35012575
http://dx.doi.org/10.1186/s13024-021-00510-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751314/
https://www.ncbi.nlm.nih.gov/pubmed/35012575
http://dx.doi.org/10.1186/s13024-021-00510-y

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