Phiclust: a clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations

The ability to discover new cell phenotypes by unsupervised clustering of single-cell transcriptomes has revolutionized biology. Currently, there is no principled way to decide whether a cluster of cells contains meaningful subpopulations that should be further resolved. Here, we present phiclust (ϕ...

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Detalles Bibliográficos
Autores principales: Mircea, Maria, Hochane, Mazène, Fan, Xueying, Chuva de Sousa Lopes, Susana M., Garlaschelli, Diego, Semrau, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751334/
https://www.ncbi.nlm.nih.gov/pubmed/35012604
http://dx.doi.org/10.1186/s13059-021-02590-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751334/
https://www.ncbi.nlm.nih.gov/pubmed/35012604
http://dx.doi.org/10.1186/s13059-021-02590-x

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