Speed dating for enzymes! Finding the perfect phosphopantetheinyl transferase partner for your polyketide synthase

The biosynthetic pathways for the fungal polyketides bikaverin and bostrycoidin, from Fusarium verticillioides and Fusarium solani respectively, were reconstructed and heterologously expressed in S. cerevisiae alongside seven different phosphopantetheinyl transferases (PPTases) from a variety of ori...

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Detalles Bibliográficos
Autores principales: Pedersen, Tobias Bruun, Nielsen, Mikkel Rank, Kristensen, Sebastian Birkedal, Spedtsberg, Eva Mie Lang, Sørensen, Trine, Petersen, Celine, Muff, Jens, Sondergaard, Teis Esben, Nielsen, Kåre Lehmann, Wimmer, Reinhard, Gardiner, Donald Max, Sørensen, Jens Laurids
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751348/
https://www.ncbi.nlm.nih.gov/pubmed/35012550
http://dx.doi.org/10.1186/s12934-021-01734-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751348/
https://www.ncbi.nlm.nih.gov/pubmed/35012550
http://dx.doi.org/10.1186/s12934-021-01734-9

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