NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

Objective: To investigate the effect of NAD+ on thymus autophagy in experimental autoimmune encephalomyelitis (EAE) mice through SIRT1. Methods: Bioinformatic analysis was used to identify hub genes. Forty female C57BL/6 mice were randomly divided into 4 groups: control, EAE, NAD+, and NAD+ +SIRT1 i...

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Detalles Bibliográficos
Autores principales: Wang, Jinli, Song, Xueqin, Tan, Guojun, Sun, Pengtao, Guo, Li, Zhang, Ning, Wang, Jueqiong, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751589/
https://www.ncbi.nlm.nih.gov/pubmed/34928817
http://dx.doi.org/10.18632/aging.203781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751589/
https://www.ncbi.nlm.nih.gov/pubmed/34928817
http://dx.doi.org/10.18632/aging.203781

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