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LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells

Ovarian cancer is one of the most lethal gynecologic malignancies. It has been shown that PARP inhibitors can selectively target BRCA-mutated ovarian cancer and exert some effects on ovarian cancer without BRCA mutations. However, the mechanism is still unclear. In this study, wild-type BRCA ovarian...

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Detalles Bibliográficos
Autores principales: Xiang, Jiangdong, Zhou, Lina, He, Yinyan, Wu, Sufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751605/
https://www.ncbi.nlm.nih.gov/pubmed/34919531
http://dx.doi.org/10.18632/aging.203780