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METTL14 benefits the mesenchymal stem cells in patients with steroid-associated osteonecrosis of the femoral head by regulating the m6A level of PTPN6

Imbalanced osteogenic/adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is considered the core pathological characteristic of steroid-associated osteonecrosis of the femoral head (SONFH). N6-Methyladenosine (m6A) is the most common type of RNA modification in eukaryotic cells...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Zhang, Haoping, Zheng, Jia, Jin, Yi, Wang, Donghui, Dai, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751613/
https://www.ncbi.nlm.nih.gov/pubmed/34910686
http://dx.doi.org/10.18632/aging.203778