The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

In all eutherian mammals, growth of the fetus is dependent upon a functional placenta, but whether and how the latter adapts to putative fetal signals is currently unknown. Here, we demonstrate, through fetal, endothelial, hematopoietic, and trophoblast-specific genetic manipulations in the mouse, t...

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Detalles Bibliográficos
Autores principales: Sandovici, Ionel, Georgopoulou, Aikaterini, Pérez-García, Vicente, Hufnagel, Antonia, López-Tello, Jorge, Lam, Brian Y.H., Schiefer, Samira N., Gaudreau, Chelsea, Santos, Fátima, Hoelle, Katharina, Yeo, Giles S.H., Burling, Keith, Reiterer, Moritz, Fowden, Abigail L., Burton, Graham J., Branco, Cristina M., Sferruzzi-Perri, Amanda N., Constância, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751640/
https://www.ncbi.nlm.nih.gov/pubmed/34963058
http://dx.doi.org/10.1016/j.devcel.2021.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751640/
https://www.ncbi.nlm.nih.gov/pubmed/34963058
http://dx.doi.org/10.1016/j.devcel.2021.12.005

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