Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

The COVID-19 pandemic caused by SARS-CoV-2 has been socially and economically devastating. Despite an unprecedented research effort and available vaccines, effective therapeutics are still missing to limit severe disease and mortality. Using high-throughput screening, we identify acriflavine (ACF) a...

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Detalles Bibliográficos
Autores principales: Napolitano, Valeria, Dabrowska, Agnieszka, Schorpp, Kenji, Mourão, André, Barreto-Duran, Emilia, Benedyk, Malgorzata, Botwina, Pawel, Brandner, Stefanie, Bostock, Mark, Chykunova, Yuliya, Czarna, Anna, Dubin, Grzegorz, Fröhlich, Tony, Hölscher, Michael, Jedrysik, Malwina, Matsuda, Alex, Owczarek, Katarzyna, Pachota, Magdalena, Plettenburg, Oliver, Potempa, Jan, Rothenaigner, Ina, Schlauderer, Florian, Slysz, Klaudia, Szczepanski, Artur, Greve-Isdahl Mohn, Kristin, Blomberg, Bjorn, Sattler, Michael, Hadian, Kamyar, Popowicz, Grzegorz Maria, Pyrc, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751734/
https://www.ncbi.nlm.nih.gov/pubmed/35021060
http://dx.doi.org/10.1016/j.chembiol.2021.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751734/
https://www.ncbi.nlm.nih.gov/pubmed/35021060
http://dx.doi.org/10.1016/j.chembiol.2021.11.006

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