Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4)

OBJECTIVE(S): Cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) is the most important human immune checkpoint that modulates T cells activity and brings about immune-homeostasis. Accordingly, checkpoint inhibitor cancer therapy has been approved as a growing method to block over-expressed immune...

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Detalles Bibliográficos
Autores principales: Sotoudeh, Nazli, Noormohammadi, Zahra, Habibi-Anbouhi, Mahdi, Kazemi-Lomedasht, Fatemeh, Behdani, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751747/
https://www.ncbi.nlm.nih.gov/pubmed/35083014
http://dx.doi.org/10.22038/IJBMS.2021.57774.12851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751747/
https://www.ncbi.nlm.nih.gov/pubmed/35083014
http://dx.doi.org/10.22038/IJBMS.2021.57774.12851

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