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Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4)
OBJECTIVE(S): Cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) is the most important human immune checkpoint that modulates T cells activity and brings about immune-homeostasis. Accordingly, checkpoint inhibitor cancer therapy has been approved as a growing method to block over-expressed immune...
Autores principales: | Sotoudeh, Nazli, Noormohammadi, Zahra, Habibi-Anbouhi, Mahdi, Kazemi-Lomedasht, Fatemeh, Behdani, Mahdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751747/ https://www.ncbi.nlm.nih.gov/pubmed/35083014 http://dx.doi.org/10.22038/IJBMS.2021.57774.12851 |
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