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Sirtuin 1 Mediates Protection Against Delayed Cerebral Ischemia in Subarachnoid Hemorrhage in Response to Hypoxic Postconditioning

BACKGROUND: Many therapies designed to prevent delayed cerebral ischemia (DCI) and improve neurological outcome in aneurysmal subarachnoid hemorrhage (SAH) have failed, likely because of targeting only one element of what has proven to be a multifactorial disease. We previously demonstrated that ini...

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Detalles Bibliográficos
Autores principales: Diwan, Deepti, Vellimana, Ananth K., Aum, Diane J., Clarke, Julian, Nelson, James W., Lawrence, Molly, Han, Byung Hee, Gidday, Jeffrey M., Zipfel, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751859/
https://www.ncbi.nlm.nih.gov/pubmed/34622677
http://dx.doi.org/10.1161/JAHA.121.021113